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Topical atropine is often prescribed for uveitis due to its effectiveness in reducing inflammation and pain associated with this condition. Uveitis involves inflammation of the uveal tract, which can lead to discomfort, spasms of the iris, and the potential for complications such as synechiae ( adhesions between the iris and the lens).

Atropine, an anticholinergic agent, works by dilating the pupil and paralyzing the ciliary body. This helps to alleviate pain by preventing the iris from spasming and allows for more comfort in the patient. Additionally, dilation of the pupil can help prevent the development of synechiae, which can occur when the inflamed iris sticks to the lens or cornea.

While other treatments such as systemic steroids or antibiotics may be part of a broader treatment regimen, atropine specifically addresses the painful symptoms and underlying inflammatory response associated with uveitis, making it a common choice in ophthalmic practice for managing this condition.